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4/19/2019 8:06:04 PM | Browse: 70 | Download: 74
Publication Name World Journal of Hepatology
Manuscript ID 44669
Country/Territory China
Category Infectious Diseases
Manuscript Type Review
Article Title Hepatitis C virus cure with direct-acting antivirals: Clinical, economic, societal and patient value for China
Manuscript Source Unsolicited Manuscript
All Author List Qing Xie, Jian-Wei Xuan, Hong Tang, Xiao-Guang Ye, Peng Xu, I-Heng Lee and Shan-Lian Hu
Funding Agency and Grant Number
Corresponding Author Shan-Lian Hu, MD, MSc, Professor, School of Public Health, Fudan University, 130 Dong’an Road, Shanghai 200032, China. shanlian_hu_doc@outlook.com
Key Words Hepatitis C; Value of cure; Sustained virologic response; End stage liver disease; Prevention of transmission; Cost-effectiveness; Patient-reported outcomes
Core Tip Chronic hepatitis C is a systemic disease that manifests both hepatically and extrahepatically, leading to impaired patient-reported outcomes (PROs) and huge economic burden on the healthcare system and society. Direct acting antivirals are effective hepatitis C therapies that improve PROs and have broad eligible patient populations, good efficacy, few adverse events, and high adherence rates. Sustained virologic response is associated with improved clinical outcomes and increased work productivity. Curative therapies for hepatis C was of substantial societal and economic value because they reduce productivity loss and avoid the management costs associated with advanced liver disease and extrahepatic manifestations.
Citation Xie Q, Xuan JW, Tang H, Ye XG, Xu P, Lee IH, Hu SL. Hepatitis C virus cure with direct-acting antivirals: Clinical, economic, societal and patient value for China. World J Hepatol 2019; 11(5): 421-441
Received
2018-12-28 09:14
Peer-Review Started
2018-12-29 13:07
To Make the First Decision
2019-02-18 01:42
Return for Revision
2019-03-05 00:57
Revised
2019-04-18 14:40
Second Decision
2019-04-19 07:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-04-19 20:06
Articles in Press
2019-04-19 20:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-05-25 07:16
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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