Publication Name	World Journal of Clinical Cases
Manuscript ID	45205
Country	United States

Category	Medicine, Research & Experimental
Manuscript Type	Case Report
Article Title	Sustained complete response to erlotinib in squamous cell carcinoma of the head and neck: A case report
Manuscript Source	Invited Manuscript
All Author List	Mie Mie Thinn, Chung-Tzu Hsueh and Chung-Tsen Hsueh
Funding Agency and Grant Number
Corresponding Author	Chung-Tsen Hsueh, MD, PhD, Professor, Division of Medical Oncology and Hematology, Department of Medicine, Loma Linda University, 11175 Campus Street, CSP 11015, Loma Linda, CA 92357, United States. chsueh@llu.edu
Key Words	Squamous cell carcinoma of head and neck; Epidermal growth factor receptor; Erlotinib; Complete response; Skin rash; Tyrosine kinase inhibitor; Case report
Core Tip	We present a patient with recurrent/metastatic squamous cell carcinoma of head and neck who had durable complete response after completion of 6-mo erlotinib treatment. Patient experienced severe skin rash and diarrhea toxicities from erlotinib. The severity of these adverse effects has been shown to be predictors of treatment response from inhibitors of epidermal growth factor receptor.
Citation	Thin MM, Hsueh CT, Hsueh CT. Sustained complete response to erlotinib in squamous cell carcinoma of the head and neck: A case report. World J Clin Cases 2019; 7(5): 616-622

Received	2018-12-19 06:35
Peer-Review Started	2018-12-20 03:05
To Make the First Decision	2019-01-07 00:25
Return for Revision	2019-01-08 07:08
Revised	2019-01-12 01:06
Second Decision	2019-01-29 06:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-01-30 02:20
Articles in Press	2019-01-30 02:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-03-05 07:56

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com