Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	45516
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Histopathological characteristics of needle core biopsy and surgical specimens from patients with solitary hepatocellular carcinoma or intrahepatic cholangiocarcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Ju-Shan Wu, Ji-Liang Feng, Rui-Dong Zhu, San-Guang Liu, Da-Wei Zhao and Ning Li
Funding Agency and Grant Number	Funding Agency Grant Number The Scientific Research Project of Beijing You'an Hospital, CCMU YNKTTS20180110 The Special Scientific Research Fund for Beijing Health Development 2014-2-2182 Capital Characteristic Fund Z171100001017035
Corresponding Author	Ning Li, MD, PhD, Professor, General Surgical Center, Beijing You-An Hospital, Capital Medical University, No. 8 Xitoutiao Outside You'anmen, Fengtai District, Beijing 100069, China. liningbjah@163.com
Key Words	Histopathological; Needle core biopsy; Surgical specimens; Solitary hepatocellular carcinoma; Intrahepatic cholangiocarcinoma
Core Tip	Pathological manifestations of hepatic tumours are often associated with prognosis. The present study was designed to evaluate the concordance of the clinicopathological characteristics and staining of three biomarker between the needle core biopsy (NCB) and surgery specimen from patients with hepatocellular carcinoma or intrahepatic cholangiocarcinoma. Our results indicated that reasonable interpretation of immunohistochemical staining results in NCB is vital for improving the accuracy of tumour diagnosis. The simplified binary classification provides an easy and applicable approach to improve the diagnostic value of hepatic malignancy in NCB samples.
Citation	Wu JS, Feng JL, Zhu RD, Liu SG, Zhao DW, Li N. Histopathological characteristics of needle core biopsy and surgical specimens from patients with solitary hepatocellular carcinoma or intrahepatic cholangiocarcinoma. World J Gastrointest Oncol 2019; 11(5): 404-415

Received	2019-01-16 01:49
Peer-Review Started	2019-01-16 04:37
To Make the First Decision	2019-03-18 06:02
Return for Revision	2019-03-19 01:21
Revised	2019-03-29 10:06
Second Decision	2019-04-18 08:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-04-19 18:15
Articles in Press	2019-04-19 18:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-05-14 02:20

ISSN	1948-5204 (online)
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