Publication Name	World Journal of Stem Cells
Manuscript ID	46595
Country	China

Category	Neurosciences
Manuscript Type	Review
Article Title	Using induced pluripotent stem cells for modeling Parkinson’s disease
Manuscript Source	Invited Manuscript
All Author List	Min-Jing Ke, Cheong-Meng Chong and Huan-Xing Su
Funding Agency and Grant Number
Corresponding Author	Huan-Xing Su, MD, PhD, Associate Professor, State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, University Northern Road, Macao 999078, China. huanxingsu@umac.mo
Key Words	Parkinson's disease; Dopaminergic neurons; Induced pluripotent stem cells; Somatic cell reprogramming; Aging;
Core Tip	Human induced pluripotent stem cell (iPSC)-derived dopaminergic neurons hold great promise for studying disease mechanisms underlying Parkinson’s disease (PD) and testing drug effects. A number of reviews have previously summarized the potential use of patient iPSCs for modeling PD. However, few of them comprehensively discuss the establishment of gene-editing-based iPSCs for PD and their application in research. Our objective is to consolidate the current literature on various iPSC-based PD models either derived from PD patients through reprogramming technology or established by gene-editing technology, and provide new insights into the application of iPSC PD models.
Citation	Ke MJ, Chong CM, Su HX. Using induced pluripotent stem cells for modeling Parkinson’s disease. World J Stem Cells 2019; 11(9):634-649

Received	2019-02-25 03:12
Peer-Review Started	2019-02-27 11:20
To Make the First Decision	2019-04-12 00:29
Return for Revision	2019-04-19 09:54
Revised	2019-07-26 07:08
Second Decision	2019-08-07 00:45
Accepted by Journal Editor-in-Chief	2019-08-07 22:58
Accepted by Company Editor-in-Chief	2019-08-21 04:14
Articles in Press	2019-08-21 04:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-17 12:04

ISSN	1948-0210 (online)
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