Publication Name	World Journal of Stem Cells
Manuscript ID	46640
Country	Slovenia

Category	Cell Biology
Manuscript Type	Review
Article Title	Presence and role of stem cells in ovarian cancer
Manuscript Source	Invited Manuscript
All Author List	Natasa Kenda Suster and Irma Virant-Klun
Funding Agency and Grant Number
Corresponding Author	Natasa Kenda Suster, MD, PhD, Attending Doctor, Surgical Oncologist, Department of Gynecology, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, Zaloska cesta 2, Ljubljana 1000, Slovenia. natasa@kenda.si
Key Words	Ovarian cancer; Cancer stem cells; Very small embryonic-like stem cells; Epithelial-mesenchymal transition; ;
Core Tip	Ovarian carcinoma, based on its biological profile and clinical course, presents a prototype of cancer stem-cell-driven disease. Ovarian cancer stem cells (CSCs) might be responsible for tumor formation, invasion, and metastasis, disease relapse and chemoresistance acquisition. For the successful treatment of this deadly disease, target therapy directed toward ovarian CSCs should be implemented. But to this, identification and characterisation of CSC subpopulations, such as very small embryonic-like stem cells, should be derived. This review’s objective is to consolidate present knowledge and to discuss future perspectives in the field of ovarian CSCs.
Citation	Kenda Suster N, Virant-Klun I. Presence and role of stem cells in ovarian cancer. World J Stem Cells 2019; 11(7): 383-397

Received	2019-02-20 03:38
Peer-Review Started	2019-02-20 06:15
To Make the First Decision	2019-04-16 06:23
Return for Revision	2019-04-17 08:40
Revised	2019-04-23 20:16
Second Decision	2019-05-24 06:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-06-13 02:57
Articles in Press	2019-06-13 02:57
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-07-04 19:21
Typeset the Manuscript	2019-07-25 03:06

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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