Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	46768
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Premalignant lesions and gastric cancer: Current understanding
Manuscript Source	Invited Manuscript
All Author List	Athanasios Koulis, Andrew Buckle and Alex Boussioutas
Funding Agency and Grant Number
Corresponding Author	Alex Boussioutas, FRACP, MBBS, MD, PhD, Professor, Upper Gastrointestinal Translational Laboratory, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Victoria 8006, Australia. alex.boussioutas@petermac.org
Key Words	Helicobacter pylori; Correa cascade; Atrophic gastritis; Intestinal metaplasia; Point of no return; Dysplasia
Core Tip	Despite recent advances in our understanding of the molecular and cellular events involved in gastric cancer, little is known about how gastric premalignant lesions actually lead to this usually lethal disease (5 years survival about 20% in most Western countries). It is still not clear whether some or all of these lesions are directly involved in the process of gastric carcinogenesis or whether they are simply bystanders. In this review, we attempt to shed some light into how our current understanding of premalignant lesions may be used to improve patient stratification and lead to better overall patient survival rates.
Citation	Athanasios Koulis, Andrew Buckle, Alex Boussioutas. Premalignant lesions and gastric cancer: Current understanding. World J Gastrointest Oncol 2019; 11(9): 665-678

Received	2019-02-25 01:56
Peer-Review Started	2019-02-26 00:59
To Make the First Decision	2019-04-16 06:49
Return for Revision	2019-04-19 07:05
Revised	2019-05-29 14:22
Second Decision	2019-08-16 08:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-08-21 02:55
Articles in Press	2019-08-21 02:55
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-09-01 23:01
Typeset the Manuscript	2019-09-07 04:01

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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