Publication Name	World Journal of Gastroenterology
Manuscript ID	46852
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Recurrent renal cell carcinoma leading to a misdiagnosis of polycystic liver disease: A case report
Manuscript Source	Invited Manuscript
All Author List	Chen Liang, Kazuhiro Takahashi, Masanao Kurata, Shingo Sakashita, Tatsuya Oda and Nobuhiro Ohkohchi
Funding Agency and Grant Number
Corresponding Author	Kazuhiro Takahashi, MD, PhD, Doctor, Department of Surgery, University of Tsukuba, Tennoudai 1-1-1, Tsukuba 3058575, Ibaraki Prefecture, Japan. kazu1123@hh.iij4u.or.jp
Key Words	Polycystic liver disease; Polycystic kidney disease; Cystic metastasis; Renal cell carcinoma; Case report
Core Tip	Polycystic liver disease (PCLD) usually exhibits typical presentations in imaging studies, but the diagnosis is sometimes challenging because of the late onset of this genetic disorder and the atypical presentations of other diseases. In a case of cystic metastasis of renal cell carcinoma, the disease could be misdiagnosed as PCLD due to the clinical and radiological similarity between these disorders. This case demonstrates that when multiple cystic lesions are observed in the liver, it is important to first exclude the cystic metastasis of a cancer. Additionally, some specific types of cancer can have different presentations at metastasis and recurrence.
Citation	Liang C, Takahashi K, Kurata M, Sakashita S, Oda T, Ohkohchi N. Recurrent renal cell carcinoma leading to a misdiagnosis of polycystic liver disease: A case report. World J Gastroenterol 2019; 25(18): 2264-2270

Received	2019-03-06 06:04
Peer-Review Started	2019-03-06 08:36
To Make the First Decision	2019-04-08 00:48
Return for Revision	2019-04-08 07:27
Revised	2019-04-17 01:28
Second Decision	2019-04-19 07:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-04-20 01:53
Articles in Press	2019-04-20 01:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-05-14 00:29

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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