Publication Name	World Journal of Gastroenterology
Manuscript ID	47132
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Basic Study
Article Title	Silicone-covered biodegradable magnesium stent for treating benign esophagus stricture in rabbit model
Manuscript Source	Unsolicited Manuscript
All Author List	Kai Yang, Jun Cao, Tian-Wen Yuan, Yue-Qi Zhu, Bi Zhou and Ying-Sheng Cheng
Funding Agency and Grant Number
Corresponding Author	Ying-Sheng Cheng, MD, Academic Fellow, Doctor, Department of Intervention Radiology, Shanghai Sixth People's Hospital East Campus Affiliated to Shanghai Jiao-tong University, No.222, W-huanhu No.3 Road, Shanghai 201306, China. chengyingsheng@hotmail.com
Key Words	Benign esophageal stricture; Biodegradable stent; Magnesium; Silicone membrane
Core Tip	Stent insertion can be a safe, easy and effective alleviate the symptoms of benign esophageal strictures (BES). But the metallic stents implantation is associated with some severe complications, such as migration, tissue ingrowth, and in-stent restenosis. Biodegradable stent has been used as an effective and accepted method to treat BES. We fabricated a silicone-covered biodegradable magnesium stent, and evaluated technical feasibility, tissue reaction and stent degradation for treating benign esophageal stricture in rabbit model. We found that implantation of silicone-covered magnesium stent provided reliable support for at least two weeks and were a promising strategy to treatment benign esophageal stricture.
Citation	Yang K, Cao J, Yuan TW, Zhu YQ, Zhou B, Cheng YS. Silicone-covered biodegradable magnesium stent for treating benign esophagus stricture in rabbit model. World J Gastroenterol 2019;25(25): 3207-3217

Received	2019-03-06 09:33
Peer-Review Started	2019-03-07 01:29
To Make the First Decision	2019-04-08 00:39
Return for Revision	2019-04-08 06:56
Revised	2019-05-14 14:11
Second Decision	2019-06-05 10:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-06-08 15:05
Articles in Press	2019-06-08 15:05
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-06-18 09:07
Typeset the Manuscript	2019-07-04 07:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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