Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	47852
Country	China

Category	Oncology
Manuscript Type	Case Control Study
Article Title	Protein expression trends of DNMT1 in gastrointestinal diseases: From benign to precancerous lesions to cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Tian-Miao Ma, Li-Ping Sun, Nan-Nan Dong, Ming-Jun Sun and Yuan Yuan
Funding Agency and Grant Number
Corresponding Author	Yuan Yuan, MD, PhD, Assistant Professor, Professor, Research Fellow, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, The First Hospital of China Medical University, Tumor Etiology and Screening Department of Cancer Institute and General Surgery, the First Affiliated Hospital of China Medical University. yuanyuan@cmu.edu.cn, Shenyang 110001, Liaoning Province, China. yuanyuan@cmu.edu.cn
Key Words	Gastric cancer; Colorectal cancer; DNMT1; Precancerous lesion; Intraepithelial neoplasia;
Core Tip	The expression of DNMT1 was significantly effective for screening precancerous lesions and cancers. DNMT1 could be a potential marker for the diagnosis of gastric cancer and colorectal cancer. At the same time, the fluctuation of its expression may suggest the progression of gastrointestinal diseases, which could be instructive for further examination and treatment.
Citation	Ma TM, Sun LP, Dong NN, Sun MJ, Yuan Y. Protein expression trends of DNMT1 in gastrointestinal diseases: From benign to precancerous lesions to cancer. World J Gastrointest Oncol 2019; 11(12): 1141-1150

Received	2019-03-30 04:37
Peer-Review Started	2019-04-03 09:59
To Make the First Decision	2019-08-01 00:13
Return for Revision	2019-08-28 06:36
Revised	2019-09-04 09:15
Second Decision	2019-09-12 10:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-09-13 16:15
Articles in Press	2019-09-13 16:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-09-24 09:12
Typeset the Manuscript	2019-10-27 07:45

ISSN	1948-5204 (online)
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