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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 48207
Country United States
Category Oncology
Manuscript Type Retrospective Study
Article Title Multi-institutional retrospective analysis of FOLFIRI in patients with advanced biliary tract cancers
Manuscript Source Unsolicited Manuscript
All Author List Jonathan D Mizrahi, Valerie Gunchick, Kabir Mody, Lianchun Xiao, Phani Keerthi Surapaneni, Rachna T Shroff and Vaibhav Sahai
Funding Agency and Grant Number
Corresponding Author Jonathan D Mizrahi, MD, Academic Fellow, Division of Cancer Medicine, the University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 463, Houston, TX 77030, United States. jdmizrahi@mdanderson.org
Key Words Biliary tract neoplasms; Fluorouracil; Irinotecan; Cholangiocarcinoma; Retrospective studies;
Core Tip We retrospectively analysed patients with advanced biliary tract cancers treated with 5-fluorouracil plus irinotecan at three institutions, MD Anderson, University of Michigan and Mayo Clinic in Jacksonville. We identified 98 patients with a median age of 60 years, most of whom (72%) had intrahepatic cholangiocarcinoma. Fifty and 36 patients were treated in the second and third-line settings, respectively. The median progression-free survival and overall survival were 2.4 (95%CI: 1.7-3.1) and 6.6 (95%CI: 4.7-8.4) mo, respectively.
Citation Mizrahi JD, Gunchick V, Mody K, Xiao L, Surapaneni P, Shroff RT, Sahai V. Multi-institutional retrospective analysis of FOLFIRI in patients with advanced biliary tract cancers. World J Gastrointest Oncol 2020; 12(1): 83-91
Received
2019-05-08 04:14
Peer-Review Started
2019-05-10 02:44
To Make the First Decision
2019-08-01 00:14
Return for Revision
2019-08-02 07:13
Revised
2019-08-09 19:44
Second Decision
2019-09-12 10:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-09-13 15:49
Articles in Press
2019-09-13 15:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-10-31 05:40
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved.
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