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6/10/2019 10:04:55 PM | Browse: 248 | Download: 440
Publication Name World Journal of Meta-Analysis
Manuscript ID 48225
Country China
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Adjuvant and neoadjuvant treatment vs surgery alone for resectable pancreatic cancer: A network meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Pu Shen, Kai-Jun Huang, Chuan-Zhao Zhang, Li Xiao and Tao Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
Medical Scientific Research Foundation of Guangdong Province A2017229
Corresponding Author Tao Zhang, MD, Doctor, Professor, Department of Anesthesia, the First Affiliated Hospital, Sun Yat-sen University, No.58 Zhongshan II Road, Guangzhou 510080, Guangdong Province, China. zhangt45@mail2.sysu.edu.cn
Key Words Pancreatic cancer; Surgery; Network meta-analysis; Adjuvant therapy; Neoadjuvant therapy
Core Tip No consensus is available in previous studies about the most beneficial treatment option for resectable pancreatic cancer. This is the first network meta-analysis comparing the efficiency of surgery alone, neoadjuvant chemotherapy (CT), neoadjuvant chemoradiotherapy (CRT), adjuvant CT and adjuvant CRT. We investigated these treatment options in terms of overall survival and toxicity. We find that surgery with adjuvant CT prolongs overall survival compared with surgery alone and surgery with adjuvant CRT. Surgery with adjuvant CT is the optimal treatment for resectable pancreatic cancer.
Citation Shen P, Huang KJ, Zhang CZ, Xiao L, Zhang T. Adjuvant and neoadjuvant treatment vs surgery alone for resectable pancreatic cancer: A network meta-analysis. World J Meta-Anal 2019; 7(6): 309-322
Received
2019-04-13 05:55
Peer-Review Started
2019-04-15 06:02
To Make the First Decision
2019-05-29 00:48
Return for Revision
2019-05-29 09:36
Revised
2019-06-04 15:09
Second Decision
2019-06-10 03:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-06-10 22:04
Articles in Press
2019-06-10 22:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-06-17 05:28
Typeset the Manuscript
2019-06-25 00:58
ISSN 2308-3840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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