Publication Name	World Journal of Gastroenterology
Manuscript ID	48242
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Quantitative diffusion-weighted magnetic resonance-enterography in ileal Crohn's disease: Systematic analysis of intra and interobserver reproducibility
Manuscript Source	Unsolicited Manuscript
All Author List	Hao Yu, Ya-Qi Shen, Fang-Qin Tan, Zi-Ling Zhou, Zhen Li, Dao-Yu Hu and John N Morelli
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 81571642 National Natural Science Foundation of China No. 81701657 National Natural Science Foundation of China No. 81771801 Fundamental Research Funds for the Central Universities NO.2017KFYXJJ126
Corresponding Author	Dao-Yu Hu, MD, PhD, Doctor, Professor, Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, Hubei, China. daoyuhu@hust.edu.cn
Key Words	Magnetic resonance imaging; Diffusion weighted imaging; Crohn's disease; Ileum; Reproducibility
Core Tip	We evaluated the measured reproducibility of quantitative apparent diffusion coefficients (ADC) and signal contrast ratio (SR) of terminal ileum to ipsilateral psoas muscle on b = 800 s/mm2 diffusion weighted imaging (DWI). The intra and interobserver reproducibility of ADC and SR values was good to excellent for Crohn’s disease (CD) and normal control subjects. Quantitative parameters of ADC and SR derived from DWI had outstanding diagnostic efficacy for the CD. Therefore, both ADC and SR could serve as robust and efficient quantitative biomarkers for the evaluation of CD.
Citation	Yu H, Shen YQ, Tan FQ, Zhou ZL, Li Z, Hu DY, Morelli JN. Quantitative diffusion-weighted magnetic resonance-enterography in ileal Crohn's disease: Systematic analysis of intra and interobserver reproducibility. World J Gastroenterol 2019; 25(27): 3619-3633

Received	2019-04-17 02:59
Peer-Review Started	2019-04-17 06:39
To Make the First Decision	2019-05-14 02:07
Return for Revision	2019-05-14 04:52
Revised	2019-05-20 03:10
Second Decision	2019-06-05 10:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-06-08 14:54
Articles in Press	2019-06-08 14:54
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-06-17 09:42
Typeset the Manuscript	2019-07-17 00:52

ISSN	1007-9327 (print) and 2219-2840 (online)
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