Publication Name	World Journal of Clinical Cases
Manuscript ID	48557
Country	China

Category	Hematology
Manuscript Type	Case Report
Article Title	Severe serous cavity bleeding caused by acquired factor V deficiency associated with lymphatic leakage in a hemodialysis patient: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Bo Zhao, Yan-Ru Chen, Dan Luo, Hong-Chun Lin, Bing Long, Zhen-Yu Wu and Hui Peng
Funding Agency and Grant Number
Corresponding Author	Hui Peng, MD, PhD, Professor, Department of Nephrology, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Guangzhou 510630, Guangdong Province, China. pengh@mail.susu.edu.cn
Key Words	Acquired factory V deficiency; Lymphatic leakage; Serous cavity bleeding; Hemodialysis; Case report;
Core Tip	Acquired factor V deficiency (AFVD) is a rare secondary hemorrhagic disease, which can lead to serious bleeding disorder. We report a new AVFD case of a hemodialysis patient with severe serous cavity hemorrhagic effusion, associated with potentially secondary to lymphatic leakage, and factor V inhibitor detection is negative. This is the first report regarding the association between coagulation factor V deficiency and lymphatic drainage in hemodialysis patient of chronic kidney disease patient. Careful follow-up of blood coagulation is needed in patients under the treatment of lymphatic drainage.
Citation	Zhao WB, Chen YR, Luo D, Lin HC, Long B, Wu ZY, Peng H. Severe serous cavity bleeding caused by acquired factor V deficiency associated with lymphatic leakage in a hemodialysis patient: A case report. World J Clin Cases 2019; 7(17):2556-2561

Received	2019-04-24 00:38
Peer-Review Started	2019-05-08 04:04
To Make the First Decision	2019-06-03 03:15
Return for Revision	2019-06-17 03:01
Revised	2019-07-30 14:25
Second Decision	2019-08-16 10:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-08-20 04:06
Articles in Press	2019-08-20 04:06
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-08-28 13:31
Typeset the Manuscript	2019-09-05 07:13

ISSN	2307-8960 (online)
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