Publication Name	World Journal of Nephrology
Manuscript ID	48637
Country	India

Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	WNT/β-catenin signaling in urothelial carcinoma of bladder
Manuscript Source	Invited Manuscript
All Author List	Minal Garg and Niharika Maurya
Funding Agency and Grant Number
Corresponding Author	Minal Garg, MSc, PhD, Assistant Professor, Doctor, Department of Biochemistry, University of Lucknow, University Road, Lucknow 226007, India. minal14@yahoo.com
Key Words	Chemoresistance; Therapeutic approaches; Urothelial carcinoma of bladder; Urothelial cancer stem cells; Wnt/β-catenin;
Core Tip	Wnt/β-catenin signaling pathway plays significant role in maintaining balance between stemness and differentiation in adult stem cell niches. Mutations/epigenetic alterations in the regulatory components of Wnt/β-catenin signaling lead to acquisition of urothelial cancer stem cell phenotype, chemoresistance and enhanced survival. Key regulatory molecules of Wnt/β-catenin pathways are being examined as diagnostic/ prognostic markers as well as novel therapeutic targets in urothelial tumorigenesis.
Citation	Garg M, Maurya N. WNT/β-catenin signaling in urothelial carcinoma of bladder. World J Nephrol 2019;8(5): 83-94

Received	2019-04-26 01:40
Peer-Review Started	2019-05-09 02:03
To Make the First Decision	2019-08-08 07:59
Return for Revision	2019-08-08 08:26
Revised	2019-08-14 08:51
Second Decision	2019-09-04 07:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-09-16 01:25
Articles in Press	2019-09-16 01:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-09-18 06:36

ISSN	2220-6124 (online)
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