Publication Name	World Journal of Clinical Cases
Manuscript ID	49766
Country	China

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Case Report
Article Title	Recurrent hypotension induced by sacubitril/valsartan in cardiomyopathy secondary to Duchenne muscular dystrophy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Min Li and Han Chen
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Zhejiang Province LQ16H020004
Corresponding Author	Han Chen, MD, PhD, Doctor, Department of Cardiology, Zhejiang Provincial Key Laboratory of Cardiovascular Disease Diagnosis and Treatment, The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou 310009, Zhejiang Province, China. chenhanzju@zju.edu.cn
Key Words	Sacubitril/valsartan; Duchenne muscular dystrophy; Heart failure; Hypotension; Case report;
Core Tip	A 15-year-old boy with Duchenne muscular dystrophy presented to the hospital due to recurrent orthopnea for 6 mo. He was diagnosed with heart failure and was prescribed oral diuretics and digoxin at the outpatient clinic, but symptoms did not resolve. Sacubitril/valsartan was added to his therapeutic regimen 1 mo ago but resulted in recurrent hypotension and palpitation episodes until discontinuation of this medication. Although sacubitril/valsartan has been shown to be beneficial for heart failure with a reduced ejection fraction, hypotension is a common side effect of this medication, and blood pressure should be closely monitored in DMD patients with advanced heart failure.
Citation	Li JM, Chen H. Recurrent hypotension induced by sacubitril/valsartan in cardiomyopathy secondary to Duchenne muscular dystrophy: A case report. World J Clin Cases 2019; 7(23): 4098-4105

Received	2019-06-20 00:23
Peer-Review Started	2019-06-26 13:46
To Make the First Decision
Return for Revision	2019-11-12 01:32
Revised	2019-11-17 12:15
Second Decision	2019-11-19 09:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-19 21:07
Articles in Press	2019-11-19 21:07
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-11-25 05:24
Typeset the Manuscript	2019-12-03 04:05

ISSN	2307-8960 (online)
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