Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	50012
Country	Ecuador

Category	Gastroenterology & Hepatology
Manuscript Type	Clinical Trials Study
Article Title	High-definition optical magnification with digital chromoendoscopy detects gastric mucosal changes in dyspeptic-patients
Manuscript Source	Unsolicited Manuscript
All Author List	Carlos Robles-Medranda, Manuel Valero, Miguel Puga-Tejada, Roberto Oleas, Jorge Baquerizo-Burgos, Miguel Soria-Alcivar, Haydee Alvarado-Escobar and Hannah Pitanga-Lukashok
Funding Agency and Grant Number
Corresponding Author	Carlos Robles-Medranda, MD, Chief Doctor, Professor, Gastroenterology and Endoscopy Division, Instituto Ecuatoriano de Enfermedades Digestivas (IECED), Av. Abel Romeo Castillo y Av. Juan Tanca Marengo, Torre Vitalis, Mezzanine 3, Guayaquil 090505, Ecuador. carlosoakm@yahoo.es
Key Words	Gastritis; Helicobacter pylori; Gastric mucosa; Atrophic; Endoscopy; Digestive system
Core Tip	The accurate and reliable detection of Helicobacter pylori-associated gastritis and gastric atrophy is imperative for appropriate therapy, preventing the development of gastric neoplasia. Digital chromoendoscopy with optical magnification improved the identification of mucosal superficial and vascular patterns in the gastric mucosa of dyspeptic patients. We described a high sensitivity and accuracy for predicting normal gastric mucosa and Helicobacter pylori-associated gastritis, with a high interobserver agreement. The accurate detection of gastric infection by Helicobacter pylori and the presence of premalignant lesion at an early stage are important for the effective provision of treatment.
Citation	Robles-Medranda C, Valero M, Puga-Tejada M, Oleas R, Baquerizo-Burgos J, Soria-Alcívar M, Alvarado-Escobar H, Pitanga-Lukashok H. High-definition optical magnification with digital chromoendoscopy detects gastric mucosal changes in dyspeptic-patients. World J Gastrointest Endosc 2020; 12(1): 23-32

Received	2019-06-28 00:25
Peer-Review Started	2019-06-29 03:02
To Make the First Decision	2019-08-05 06:14
Return for Revision	2019-08-07 08:38
Revised	2019-08-13 16:14
Second Decision	2019-11-15 07:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-19 04:39
Articles in Press	2019-11-19 04:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-12-11 08:02

ISSN	1948-5190 (online)
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