Publication Name	World Journal of Gastroenterology
Manuscript ID	50590
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	LncRNA-SNHG15 accelerates the development of hepatocellular carcinoma by targeting miR-490-3p/HDAC2 axis
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Dai, Jia-Liang Dai, Mao-Hua Tang, Mu-Shi Ye and Shuo Fang
Funding Agency and Grant Number
Corresponding Author	Shuo Fang, PhD, Attending Doctor, The Seventh Affiliated Hospital, Sun Yat-sen University, No. 628, Zhenyuan Road, Xinhu Street, Guangming New District, Shenzhen 518107, Guangdong, China. shuofangzhongshan@163.com
Key Words	SNHG15; MiR-490-3p; Hepatocellular carcinoma; HDAC2; Pathogenesis; Regulatory mechanism
Core Tip	LncRNA-SNHG15 is up-regulated in tissue and cell lines of hepatocellular carcinoma. Hepatocellular carcinoma patients with up-regulated lncRNA-SNHG15 level were more probably had larger tumor size, and advanced clinical stage. LncRNA-SNHG15 promotes cell proliferation, migration and invasion in HCC cell lines. MiR-490-3p/HDAC2 axis was determined to be the target regulated by lncRNA-SNHG15 in hepatocellular carcinoma, and the regulatory mechanism of lncRNA-SNHG15 has been preliminarily illuminated in HCC.
Citation	Dai W, Dai JL, Tang MH, Ye MS, Fang S. LncRNA-SNHG15 accelerates the development of hepatocellular carcinoma by targeting miR-490-3p/HDAC2 axis. World J Gastroenterol 2019; 25(38): 5789-5799

Received	2019-07-29 09:05
Peer-Review Started	2019-07-29 09:06
To Make the First Decision	2019-08-19 00:33
Return for Revision	2019-08-23 09:21
Revised	2019-08-30 00:52
Second Decision	2019-09-12 09:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-09-13 04:12
Articles in Press	2019-09-13 04:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-09-16 21:12
Typeset the Manuscript	2019-10-14 01:52

ISSN	1007-9327 (print) and 2219-2840 (online)
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