Publication Name	World Journal of Clinical Cases
Manuscript ID	50743
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Case Report
Article Title	Diffuse large B cell lymphoma with bilateral adrenal and hypothalamic involvement: A case report and literature review
Manuscript Source	Unsolicited Manuscript
All Author List	Ping An, Kang Chen, Guo-Qing Yang, Jing-Tao Dou, Yu-Long Chen, Xin-Ye Jin, Xian-Ling Wang, Yi-Ming Mu and Quan-Shun Wang
Funding Agency and Grant Number
Corresponding Author	Kang Chen, MD, PhD, Doctor, Department of Endocrinology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China. cycon_ck@yeah.net
Key Words	Non-Hodgkin’s lymphoma; Bilateral adrenal glands; Hypothalamus; Panhypopituitarism; Case report;
Core Tip	The synchronous involvement of 2 endocrine organs is very rare in Non-Hodgkin’s lymphoma (NHL). This is the first case of NHL with bilateral adrenal gland and hypothalamic involvement that caused adrenocortical insufficiency and panhypopituitarism. The presentation created a diagnostic dilemma, which was resolved by determination of various endocrine hormone levels, biopsy, and 18fluorine-fluorodeoxyglucose positron emission tomography/computed tomography. This article aims to discuss the treatment approaches available when a patient with NHL has multiple endocrine organs involved. This information can help physicians with misdiagnosis prevention.
Citation	An P, Chen K, Yang GQ, Dou JT, Chen YL, Jin XY, Wang XL, Mu YM, Wang QS. Diffuse large B cell lymphoma with bilateral adrenal and hypothalamic involvement: A case report and literature review. World J Clin Cases 2019; 7(23): 4075-4083

Received	2019-09-07 10:35
Peer-Review Started	2019-09-07 10:36
To Make the First Decision	2019-09-27 01:15
Return for Revision	2019-10-15 03:31
Revised	2019-10-22 04:25
Second Decision	2019-11-12 11:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-13 23:42
Articles in Press	2019-11-13 23:42
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-11-28 07:22
Typeset the Manuscript	2019-12-05 01:33

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com