Publication Name	World Journal of Clinical Cases
Manuscript ID	51133
Country	China

Category	Critical Care Medicine
Manuscript Type	Observational Study
Article Title	Value of early diagnosis of sepsis complicated with acute kidney injury by renal contrast-enhanced ultrasound
Manuscript Source	Unsolicited Manuscript
All Author List	Xiu-Yan Wang, Yan-Ping Pang, Tian Jiang, Shuo Wang, Jiang-Tao Li, Bao-Min Shi and Chen Yu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81873609
Corresponding Author	Bao-Min Shi, MD, PhD, Chief Physician, Professor, Department of General Surgery, Tongji Hospital of Tongji University, No. 389 Xincun Road, Putuo District, Shanghai 200065, China. baominsph@163.com
Key Words	Sepsis; Acute kidney injury; Serum creatinine; Contrast-enhanced ultrasound; Peak intensity; Wash in slope
Core Tip	Early detection of risk factors for septic acute kidney injury (AKI) and early intervention are important for the treatment of patients with sepsis. Currently, serum creatinine (SCr) is used as the criterion for AKI diagnosis. But SCr has obvious hysteresis and poor sensitivity, and it is difficult to predict the occurrence of early septic AKI. In this study, contrast-enhanced ultrasound techniques was utilized to explore the value of early diagnosis of septic AKI and it revealed that the combination of SCr, peak intensity and wash in slope (contrast-enhanced ultrasound indicators) can improve the early diagnosis of septic AKI.
Citation	Wang XY, Pang YP, Jiang T, Wang S, Li JT, Shi BM, Yu C. Value of early diagnosis of sepsis complicated with acute kidney injury by renal contrast-enhanced ultrasound. World J Clin Cases 2019; 7(23): 3934-3944

Received	2019-09-06 00:17
Peer-Review Started	2019-09-06 00:17
To Make the First Decision	2019-10-24 09:27
Return for Revision	2019-10-30 01:12
Revised	2019-10-30 07:37
Second Decision	2019-11-19 09:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-11-19 21:01
Articles in Press	2019-11-19 21:01
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-11-30 23:35
Typeset the Manuscript	2019-12-05 01:54

ISSN	2307-8960 (online)
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