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Publication Name World Journal of Gastroenterology
Manuscript ID 52126
Country China
Category Public, Environmental & Occupational Health
Manuscript Type Retrospective Study
Article Title Prevalence, clinical characteristics, risk factors, and indicators for lean Chinese adults with nonalcoholic fatty liver disease
Manuscript Source Invited Manuscript
All Author List Jing Zeng, Rui-Xu Yang, Chao Sun, Qin Pan, Rui-Nan Zhang, Guang-Yu Chen, Ying Hu and Jian-Gao Fan
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research and Development Plan “Precision Medicine Research” 2017YFSF090203
National Natural Science Foundation of China 81873565
National Natural Science Foundation of China 81900507
Hospital Funded Clinical Research, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 17CSK04
Hospital Funded Clinical Research, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine 15LC06
Corresponding Author Jian-Gao Fan, MD, PhD, Professor, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Children’s Digestion and Nutrition, No. 1665, Kongjiang Road, Yangpu District, Shanghai 200092, China. fanjiangao@xinhuamed.com.cn
Key Words Non-alcoholic fatty liver disease; Lean; Body max index; Waist circumference; Fatty liver index; Triglyceride
Core Tip The precise characterizations of nonalcoholic fatty liver disease (NAFLD) in lean Chinese adults with normal waist circumference (WC) remain unclear. Therefore, we aimed to investigate the prevalence, clinical characterizations, risk factors and possible indicators for NAFLD in this. Among 810 lean participants with normal WC, 142 (17.5%) fulfilled the diagnostic criteria for NAFLD. NAFLD is not uncommon in Chinese lean adults even with normal WC. Metabolic factors may play important roles in this NAFLD rather than genetic factors. A lower cut-off value of the fatty liver index score in screening for NAFLD may be used for Chinese lean adults with normal WC.
Citation Zeng J, Yang RX, Sun C, Pan Q, Zhang RN, Chen GY, Hu Y, Fan JG. Prevalence, clinical characteristics, risk factors, and indicators for lean Chinese adults with nonalcoholic fatty liver disease. World J Gastroenterol 2020; 26(15): 1792-1804
Received
2019-12-25 05:06
Peer-Review Started
2019-12-25 05:07
To Make the First Decision
Return for Revision
2020-01-19 01:13
Revised
2020-03-19 16:59
Second Decision
2020-03-26 12:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-26 21:06
Articles in Press
2020-03-26 21:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-04-01 02:55
Typeset the Manuscript
2020-04-20 02:02
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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