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Articles in Press
1/18/2020 6:47:34 PM | Browse: 410 | Download: 328
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Prospective Study |
Article Title |
Technetium-99m-labeled macroaggregated albumin lung perfusion scan for diagnosis of hepatopulmonary syndrome: A prospective study comparing brain uptake and whole-body uptake
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
He Zhao, Jiaywei Tsauo, Xiao-Wu Zhang, Huai-Yuan Ma, Ning-Na Weng, Gong-Shun Tang and Xiao Li |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Key R and D Program of China |
2017YFC0107800 |
CAMS Initiative for Innovative Medicine |
2016-12M-2-004 |
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Corresponding Author |
Xiao Li, MD, PhD, Doctor, Postdoc, Professor, Department of Interventional Therapy, National Cancer Center/National Clinical Research Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. simonlixiao@gmail.com |
Key Words |
Portal Hypertension; Intrapulmonary Vascular Dilations; Radionuclide Imaging; Technetium-99m-labeled Macroaggregated albumin Lung Perfusion Scan; Diagnostic Tests; Sensitivity and Specificity |
Core Tip |
Hepatopulmonary syndrome is a common complication of liver disease which impairs the lungs’ ability to oxygenate blood, leading to debilitating symptoms, such as shortness of breath. Intrapulmonary vascular dilations, a hallmark of hepatopulmonary syndrome, can be detected using technetium-99m-labeled macroaggregated albumin lung perfusion scan, however, of the two most commonly used methods of result interpretation (i.e., brain uptake and whole-body uptake), it is unclear which is more accurate. In this study of 69 patients with liver cirrhosis, we found that whole-body uptake is more accurate than brain uptake for detecting intrapulmonary vascular dilations. |
Citation |
Zhao H, Tsauo J, Zhang X, Ma H, Weng N, Tang G, Li X. Technetium-99m-labeled macroaggregated albumin lung perfusion scan for diagnosis of hepatopulmonary syndrome: A prospective study comparing brain uptake and whole-body uptake. World J Gastroenterol 2020; 26(10): 1088-1097 |
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Received |
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2019-11-14 03:03 |
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Peer-Review Started |
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2019-11-14 03:03 |
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To Make the First Decision |
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Return for Revision |
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2019-12-30 22:17 |
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Revised |
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2020-01-06 07:58 |
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Second Decision |
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2020-01-18 10:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-01-18 18:47 |
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Articles in Press |
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2020-01-18 18:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-02-19 23:18 |
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Typeset the Manuscript |
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2020-03-13 09:02 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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