| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Validation and evaluation of clinical prediction systems for first and repeated trans-arterial chemoembolization in unresectable hepatocellular carcinoma: A Chinese multicenter retrospective study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhe-Xuan Wang, En-Xin Wang, Wei Bai, Dong-Dong Xia, Wei Mu, Jing Li, Qiao-Yi Yang, Ming Huang, Guo-Hui Xu, Jun-Hui Sun, Hai-Liang Li, Hui Zhao, Jian-Bing Wu, Shu-Fa Yang, Jia-Ping Li, Zi-Xiang Li, Chun-Qing Zhang, Xiao-Li Zhu, Yan-Bo Zheng, Qiu-He Wang, Jing Li, Jie Yuan, Xiao-Mei Li, Jing Niu, Zhan-Xin Yin, Jie-Lai Xia, Dai-Ming Fan and Guo-Hong Han |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Guo-Hong Han, PhD, Professor, Department of Liver Disease and Digestive Interventional Radiology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 15 West Changle Road, Xi’an 710032, Shaanxi Province, China. hangh@fmmu.edu.cn |
| Key Words |
Trans-arterial chemoembolization; Hepatocellular carcinoma; Prognostic system; Radiological response; Overall survival; Predictive ability |
| Core Tip |
There are several prognostic systems for the prediction of treatment outcome following trans-arterial chemoembolization for hepatocellular carcinoma; however, their discriminatory abilities in real-world patients need to be validated and compared to select the optimal system for clinical decision-making. We found that the six-and-twelve criteria were closely correlated with radiological response, modified Hepatoma Arterial-embolization Prognostic version 3 predicted overall survival best, and ABCR (alpha-fetoprotein, Barcelona Clinic Liver Cancer, Child-Pugh and Response) was a reliable predictive system for post repeated trans-arterial chemoembolization survival. The sequential combination of these systems performed well in outcome prediction. |
| Citation |
Wang ZX, Wang EX, Bai W, Xia DD, Mu W, Li J, Yang QY, Huang M, Xu GH, Sun JH, Li HL, Zhao H, Wu JB, Yang SF, Li JP, Li ZX, Zhang CQ, Zhu XL, Zheng YB, Wang QH, Li J, Yuan J, Li XM, Niu J, Yin ZX, Xia JL, Fan DM, Han GH, on behalf of China HCC-TACE Study Group. Validation and evaluation of clinical prediction systems for first and repeated trans-arterial chemoembolization in unresectable hepatocellular carcinoma: A Chinese multicenter retrospective study. World J Gastroenterol 2020; 26(6): 657-669 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
