Publication Name	World Journal of Clinical Oncology
Manuscript ID	52802
Country	United States

Category	Medicine, Research & Experimental
Manuscript Type	Review
Article Title	Narrowing the focus: Therapeutic cell surface targets for refractory triple-negative breast cancer
Manuscript Source	Invited Manuscript
All Author List	Narges K Tafreshi, David L Morse and Marie Catherine Lee
Funding Agency and Grant Number
Corresponding Author	Marie Catherine Lee, FACS, MD, Surgeon, Surgical Oncologist, Comprehensive Breast Program, Moffitt Cancer Center, 12920 N. McKinley Drive, Tampa, FL 33612, United States. m.catherine.lee@moffitt.org
Key Words	Breast cancer; Triple negative; Biomarker; Cell surface; Targeted therapy; Chemorefractory
Core Tip	Triple-negative breast cancer continues to be a challenge in breast cancer therapeutics, as these heterogeneous tumors are refractory to many effective and well-tolerated standard treatments. Even more concerning is the subpopulation of these tumors that progress even on the most aggressive therapeutic regimens. The core of this work reviews the developing approaches for treatment-refractory triple-negative breast cancer and proposes cell-surface targeting as a novel modality for targeted treatment of resistant disease.
Citation	Tafreshi NK, Morse DL, Lee MC. Narrowing the focus: Therapeutic cell surface targets for refractory triple-negative breast cancer. World J Clin Oncol 2020; 11(4): 169-179

Received	2019-12-30 14:08
Peer-Review Started	2019-12-30 14:13
To Make the First Decision
Return for Revision	2020-02-20 06:07
Revised	2020-03-25 23:54
Second Decision	2020-03-27 07:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-03-30 01:42
Articles in Press	2020-03-30 01:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-04-22 06:13

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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