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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 53072
Country China
Category Biochemistry & Molecular Biology
Manuscript Type Basic Study
Article Title Potential microRNA panel for the diagnosis and prediction of overall survival of hepatocellular carcinoma with hepatitis B virus infection
Manuscript Source Unsolicited Manuscript
All Author List Qi Zhang, Hai-Feng Xu, Wen-Yue Song, Peng-Jun Zhang and Yong-Bo Song
Funding Agency and Grant Number
Funding Agency Grant Number
National Key R&D Program of China 2016YFC0106604
Corresponding Author Yong-Bo Song, PharmD, Associate Professor, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, No. 103 Wenhua Road, Shenhe District, Shenyang 110016, Liaoning Province, China. songyongbo@syphu.edu.cn
Key Words Hepatitis B virus infection; Hepatocellular carcinoma; MicroRNAs; Cirrhosis; Biomarker; Tissue
Core Tip Abnormal expression of microRNAs (miRNAs) may lead to an abnormal physiological state and disease, such as, kinds of cancers. We detect the levels of miR-375, miR-122, miR-143 and miR-224. By combination of the miRNA panels, the area under the curves of the receiver-operating-characteristic curve was 0.991. In addition, the four miRNAs (miR-375, miR-122, miR-143 and miR-224) may be helpful for early detection and prognosis of hepatocellular carcinoma.
Citation Zhang Q, Xu HF, Song WY, Zhang PJ, Song YB. Potential microRNA panel for the diagnosis and prediction of overall survival of hepatocellular carcinoma with hepatitis B virus infection. World J Gastrointest Oncol 2020; 12(4): 383-393
Received
2019-12-22 11:24
Peer-Review Started
2019-12-22 11:24
To Make the First Decision
Return for Revision
2020-01-19 04:26
Revised
2020-02-06 00:34
Second Decision
2020-03-22 04:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-24 13:21
Articles in Press
2020-03-24 13:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-04-14 06:41
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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