Publication Name	World Journal of Gastroenterology
Manuscript ID	54235
Country	Czech Republic

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Non-invasive prediction of persistent villous atrophy in celiac disease
Manuscript Source	Invited Manuscript
All Author List	Barbora Packova, Petra Kovalcikova, Zdenek Pavlovsky, Daniel Bartusek, Jitka Prokesova, Jiri Dolina and Radek Kroupa
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Health, Czech Republic FNBr, 65269705
Corresponding Author	Radek Kroupa, MD, PhD, Doctor, Research Assistant Professor, Department of Gastroenterology and Internal Medicine, University Hospital Brno, Faculty of Medicine, Masaryk University, Jihlavska 20, Brno 62500, Czech Republic. kroupa.radek@fnbrno.cz
Key Words	Celiac disease; Villous atrophy; Anti-tissue transglutaminase antibodies; Anti-deamidated gliadin peptide antibodies; Abdominal ultrasound; Gluten-free diet
Core Tip	We attempted to determine whether indicators such as anti-tissue transglutaminase antibodies (aTTG), anti-deamidated gliadin peptide antibodies (aDGP), and abdominal ultrasonography could predict villous atrophy (VA). We studied patients who were diagnosed with celiac disease and were on a gluten-free diet for at least one year; they were followed up for a maximum of four years. We determined that aTTG and aDGP were not optimal markers of persistent VA. However, we found that a combination of serology and bowel ultrasound examination enabled detection of VA with better accuracy.
Citation	Packova B, Kovalcikova P, Pavlovsky Z, Bartusek D, Prokesova J, Dolina J, Kroupa R. Non-invasive prediction of persistent villous atrophy in celiac disease. World J Gastroenterol 2020; 26(26): 3780-3791

Received	2020-01-16 21:33
Peer-Review Started	2020-01-16 21:33
To Make the First Decision
Return for Revision	2020-04-08 18:16
Revised	2020-05-13 20:55
Second Decision	2020-06-30 09:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-06-30 19:32
Articles in Press	2020-06-30 19:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-07-14 01:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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