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Articles in Press
6/27/2020 8:52:07 PM | Browse: 175 | Download: 394
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Review |
| Article Title |
Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zhan-Jun Ma, Jing-Jing Yang, Yu-Bao Lu, Zhao-Yang Liu and Xue-Xi Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chinese Medicine Administration Research Project of Gansu province |
GZK-2019-46 |
| Cuiying Technology Innovation Project of Lanzhou University Second Hospital |
CY2019-MS10 |
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| Corresponding Author |
Xue-Xi Wang, MD, Professor, School of Basic Medical Sciences, Lanzhou University, School of Medicine 205 Tianshui Rd South Lanzhou, Lanzhou 730000, Gansu Province, China. wangxuexi@lzu.edu.cn |
| Key Words |
Exosomes; Mesenchymal stem cells; Cell-free therapy; Regenerative medicine; Mesenchymal stem cell-derived exosomes; Extracellular vesicles |
| Core Tip |
Mesenchymal stem cell-derived exosomes (MSC-Exos) contain a variety of functional proteins, mRNAs, miRNAs, and signaling lipids. MSC-Exos are more stable than their parent cells and do not have the safety issues of living cells, such as tumorigenesis and occlusion of the microvasculature. MSC-Exos represent an alternative to MSC-based therapies for regenerative medicine. In this review, we summarize the characteristics of MSC-Exos and highlight their functions and therapeutic potential for tissue/organ regeneration and for kidney, liver, cardiovascular, neurological, and musculoskeletal diseases, as well as cutaneous wound healing. |
| Citation |
Ma ZJ, Yang JJ, Lu YB, Liu ZY, Wang XY. Mesenchymal stem cell-derived exosomes: Toward cell-free therapeutic strategies in regenerative medicine. World J Stem Cells 2020; 12(8): 814-840 |
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Received |
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2020-03-15 09:46 |
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Peer-Review Started |
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2020-03-15 09:47 |
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To Make the First Decision |
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Return for Revision |
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2020-04-07 22:56 |
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Revised |
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2020-04-23 10:50 |
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Second Decision |
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2020-06-22 09:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-06-27 20:52 |
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Articles in Press |
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2020-06-27 20:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-07-03 02:24 |
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Typeset the Manuscript |
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2020-08-21 15:26 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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