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Articles in Press
9/25/2020 5:24:47 AM | Browse: 114 | Download: 105
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Unremitting diarrhoea in a girl diagnosed anti-N-methyl-D-aspartate-receptor encephalitis: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Norrapat Onpoaree, Montida Veeravigrom, Anapat Sanpavat, Narissara Suratannon and Palittiya Sintusek |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Pediatric Gastroenterology and Hepatology Research Unit, Thailand |
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| Grants for Development of New Faculty Staff, Ratchadaphiseksomphot Endowment Fund, Thailand |
No. RA63/012 |
| Thailand Research Fund Thailand Science Research and Innovation, Thailand |
MRG6280190 |
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| Corresponding Author |
Palittiya Sintusek, MD, MSc, Assistant Professor, Lecturer, Division of Gastroenterology and Pediatric Gastroenterology and Hepatology Research Unit, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, 1873, Rama 4 Road, Pathumwan, Bangkok 10330, Thailand. palittiya.s@chula.ac.th |
| Key Words |
Diarrhoea; Vomiting; Autoimmune encephalitis; Children; Cytomegalovirus; Gastrointestinal |
| Core Tip |
We report a girl with behavioural change who was finally diagnosed with anti-N-methyl-D-aspartate-receptor (anti-NMDAR) encephalitis. She had unremitting vomiting and diarrhoea after 43 d of corticosteroid therapy and was later diagnosed with cytomegalovirus (CMV) esophago-enterocolitis. Surprisingly, these symptoms subsided after antiviral therapy followed by repeated pulse methylprednisolone targeting the anti-NMDAR encephalitis. CMV esophago-enterocolitis in a patient with anti-NMDAR encephalitis has not been reported before and is very rare in patients who receive only moderate-dose corticosteroids. We highlighted that immune dysregulation in autoimmune encephalitis and the linkage of anti-NMDAR receptors and the enteric nervous system might be the cause of severe gastrointestinal involvement. |
| Citation |
Onpoaree N, Veeravigrom M, Sanpavat A, Suratannon N, Sintusek P. Unremitting diarrhoea in a girl diagnosed anti-N-methyl-D-aspartate-receptor encephalitis: A case report . World J Clin Cases 2020; 8(20): 4866-4875 |
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Received |
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2020-04-15 05:57 |
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Peer-Review Started |
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2020-04-11 12:47 |
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To Make the First Decision |
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Return for Revision |
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2020-06-14 08:51 |
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Revised |
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2020-07-27 16:54 |
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Second Decision |
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2020-09-24 10:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-09-25 05:24 |
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Articles in Press |
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2020-09-25 05:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-10-12 00:58 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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