Publication Name	World Journal of Clinical Cases
Manuscript ID	56944
Country	China

Category	Infectious Diseases
Manuscript Type	Retrospective Study
Article Title	Clinical characteristics of patients with coronavirus disease 2019 presenting with gastrointestinal symptoms as initial symptoms: Retrospective case series
Manuscript Source	Unsolicited Manuscript
All Author List	Tuo-Yun Yang, Yuan-Chao Li, Si-Cong Wang, Qing-Qing Dai, Xue-Song Jiang, Shu Zuo, Liu Jia, Jun-Bo Zheng and Hong-Liang Wang
Funding Agency and Grant Number	Funding Agency Grant Number China International Medical Foundation Z-2018-35-1902
Corresponding Author	Hong-Liang Wang, MD, Department of Critical Care Medicine, the Second Affiliated Hospital of Harbin Medical University, No. 246, Xuefu Road, Nangang District, Harbin 150086, Heilongjiang Province, China. icuwanghongliang@163.com
Key Words	COVID-19; Initial symptoms; Gastrointestinal symptoms; Hospitalization; Viral transmission;
Core Tip	The objective of this retrospective case series was to characterize the clinical features of coronavirus-infected patients with gastrointestinal symptoms as initial symptoms. The clinical investigation of disease onset was underestimated, especially due to the neglection of cases presenting with gastrointestinal symptoms. We aimed to address this issue and provide an insight into the different initial symptoms between the pulmonary symptoms and gastrointestinal symptoms. Coronavirus disease 2019 patients presenting with gastrointestinal symptoms as initial symptoms need more days of viral shedding and hospitalization than the patients presenting with pulmonary symptoms.
Citation	Yang TY, Li YC, Wang SC, Dai QQ, Jiang XS, Zuo S, Jia L, Zheng JB, Wang HL. Clinical characteristics of initial symptoms presented with gastrointestinal symptoms of patients with coronavirus disease 2019: Retrospective case series. World J Clin Cases 2020; 8(14): 2950-2958

Received	2020-05-21 04:16
Peer-Review Started	2020-05-21 04:17
To Make the First Decision
Return for Revision	2020-06-04 19:53
Revised	2020-06-14 01:19
Second Decision	2020-06-30 10:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-06-30 19:22
Articles in Press	2020-06-30 19:22
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-07-06 09:33
Typeset the Manuscript	2020-07-21 02:33

ISSN	2307-8960 (online)
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