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Publication Name World Journal of Transplantation
Manuscript ID 58104
Country/Territory Sri Lanka
Category Transplantation
Manuscript Type Minireviews
Article Title Combined liver and kidney transplantation in children and long-term outcome
Manuscript Source Invited Manuscript
All Author List Randula Ranawaka, Kavinda Dayasiri and Manoji Gamage
Funding Agency and Grant Number
Corresponding Author Randula Ranawaka, MBBS, MD, Chief Physician, Senior Lecturer, Senior Researcher, Department of Paediatrics, Faculty of Medicine, University of Colombo and Lady Ridgeway Hospital for Children, Kynsey Road, Colombo 0094, Sri Lanka. rrandula@yahoo.com
Key Words Combined liver-kidney transplantation; Immunoprotection; Long-term outcomes; Renal allograft survival; Acute cellular rejection; Autosomal recessive polycystic kidney disease
Core Tip Combined liver-kidney transplantation (CLKT) is a complex surgical procedure which is increasingly performed for a number of indications, especially Primary hyperoxaluria type 1 and autosomal recessive polycystic kidney disease. In CLKT, the early mortality is mostly related to infections and surgical complications of the liver graft. On the other hand, chronic complications with liver graft are fairly rare, and the liver protects the kidney allograft from rejection, which results in stable function and long term survival of the renal allograft. Long-term outcomes are promising in children who had CLKT with good overall long-term survival rates when performed in experienced centers with expertise.
Citation Ranawaka R, Dayasiri K, Gamage M. Combined liver and kidney transplantation in children and long-term outcome. World J Transplant 2020; 10(10): 283-290
Received
2020-07-08 10:03
Peer-Review Started
2020-07-08 10:03
To Make the First Decision
Return for Revision
2020-08-22 20:23
Revised
2020-09-17 09:14
Second Decision
2020-09-25 10:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-25 18:59
Articles in Press
2020-09-25 18:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-10-08 02:28
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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