BPG is committed to discovery and dissemination of knowledge
Articles in Press
9/25/2020 5:16:09 AM | Browse: 61 | Download: 70
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Overexpression of CD155 is associated with PD-1 and PD-L1 expression on immune cells, rather than tumor cells in the breast cancer microenvironment
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui-Bin Wang, Yu-Chen Li, Quan Zhou, Shu-Zhen Lv, Ke-Yu Yuan, Jiang-Ping Wu, Yan-Jie Zhao, Qing-Kun Song and Bin Zhu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beijing Municipal Committee of Science and Technology |
Z181100001718090;Z19110006619041 |
| Beijing Municipal Administration of Hospitals |
PX2018029 |
| Beijing Shijitan Hospital, Capital Medical University |
2017-KF01 |
|
| Corresponding Author |
Bin Zhu, MD, Professor, Department of Surgical Oncology, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Haidian District, Beijing 100038, China. binbinzhu99@sohu.com |
| Key Words |
Breast cancer; CD155; PD-1; PD-L1; Tumor-infiltrating lymphocytes; Immune cells |
| Core Tip |
In this study, we showed that overexpression of CD155 in microenvironment of breast cancer had a significant association with high level of programmed cell death ligand 1 expression, exhausted CD4+ helper T cells and unexhausted CD8+ cytotoxic T cells. CD155 expression was related with the inhibitory immune microenvironment and might be an immunotherapeutic target for breast cancer. |
| Citation |
Wang RB, Li YC, Zhou Q, Lv SZ, Yuan KY, Wu JP, Zhao YJ, Song QK, Zhu B. Overexpression of CD155 is associated with PD-1 and PD-L1 expression on immune cells, rather than tumor cells in the breast cancer microenvironment. World J Clin Cases 2020; 8(23): 5935-5943 |
 |
Received |
|
2020-07-18 14:47 |
|
Peer-Review Started |
|
2020-07-18 14:48 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2020-08-21 05:08 |
|
Revised |
|
2020-08-24 13:20 |
|
Second Decision |
|
2020-09-24 12:48 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Company Editor-in-Chief |
|
2020-09-25 05:16 |
|
Articles in Press |
|
2020-09-25 05:16 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2020-10-16 02:13 |
|
Typeset the Manuscript |
|
2020-11-27 06:07 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
© 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
