Publication Name	World Journal of Clinical Cases
Manuscript ID	58785
Country	China

Category	Infectious Diseases
Manuscript Type	Case Report
Article Title	Symptomatic and optimal supportive care of critical COVID-19: A case report and literature review
Manuscript Source	Unsolicited Manuscript
All Author List	Qi-Lin Pang, Wen-Cheng He, Jin-Xiu Li and Lei Huang
Funding Agency and Grant Number	Funding Agency Grant Number Health and Family Planning Commission of Shenzhen Municipality SZLY2018024 Sanming Project of Medicine in Shenzhen SZSM201512031
Corresponding Author	Lei Huang, MD, Chief Doctor, Department of Intensive Care Unit, Peking University Shenzhen Hospital, No. 1120 Lianhua Road, Futian District, Shenzhen 518000, Guangdong Province, China. hl0248@outlook.com
Key Words	COVID-19; Critical case; Supportive treatment; Mechanical ventilation support; Case report; Literature review
Core Tip	The mortality of severe coronavirus disease 2019 (COVID-19) patients is high, and no effective antiviral drugs are available from now on. Therefore, it is important to identify a suitable treatment strategy that is associated with improved prognosis of COVID-19, especially in critically ill patients. Here, we share our experience with the treatment of one critical COVID-19 case. We conclude that timely intubation, reasonable mechanical ventilation support, appropriate anti-infection treatment, early anticoagulation and immune support and other comprehensive measures may help to reduce the course of disease and patient mortality.
Citation	Pang QL, He WC, Li JX, Huang L. Symptomatic and optimal supportive care of critical COVID-19: A case report and literature review. World J Clin Cases 2020; 8(23): 6181-6189

Received	2020-08-07 06:46
Peer-Review Started	2020-08-07 06:47
To Make the First Decision
Return for Revision	2020-08-22 23:00
Revised	2020-08-29 13:10
Second Decision	2020-09-24 13:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-09-25 05:14
Articles in Press	2020-09-25 05:14
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-10-16 00:13
Typeset the Manuscript	2020-12-01 07:48

ISSN	2307-8960 (online)
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