BPG is committed to discovery and dissemination of knowledge
Articles in Press
9/25/2020 5:26:49 AM | Browse: 48 | Download: 105
Publication Name World Journal of Gastroenterology
Manuscript ID 58981
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Nomograms and risk score models for predicting survival in rectal cancer patients with neoadjuvant therapy
Manuscript Source Unsolicited Manuscript
All Author List Fang-Ze Wei, Shi-Wen Mei, Jia-Nan Chen, Zhi-Jie Wang, Hai-Yu Shen, Juan Li, Fu-Qiang Zhao, Zheng Liu and Qian Liu
Funding Agency and Grant Number
Funding Agency Grant Number
National Key Research and Development Plan "Research on Prevention and Control of Major Chronic Noncommunicable Diseases" 2019YFC1315705
Medicine and Health Technology Innovation Project of the Chinese Academy of Medical Sciences 2017-12M-1-006
Corresponding Author Qian Liu, MD, Chief Doctor, Professor, Surgeon, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com
Key Words Neoadjuvant therapy; Rectal cancer; Nomogram; Overall survival; Disease-free survival; Risk factor score prediction model
Core Tip The manuscript focusses on the risk factors after administration of neoadjuvant therapy for locally advanced rectal cancer. The study utilized the least absolute shrinkage and selection operator and Cox regression to select risk factors for overall survival and disease-free survival and explore their prognostic value. Based on the factors, we built two nomograms and two risk factor score prediction models to predict survival time. Then, we validated the nomograms by calibration and the concordance index, and the prediction model was validated with receiver operating characteristic curves. The risk factors included in the model and nomograms can influence survival and recurrence and provide direction for clinical doctors to improve patient survival.
Citation Wei FZ, Shen HY, Mei SW, Chen JN, Wang ZJ, Zhao FQ, Li J, Liu Z, Liu Q. Nomograms and risk score models for predicting overall survival and disease-free survival in rectal cancer with neoadjuvant therapy. World J Gastroenterol 2020; 26(42): 6638-6657
Received
2020-08-18 05:53
Peer-Review Started
2020-08-18 05:53
To Make the First Decision
Return for Revision
2020-09-12 05:57
Revised
2020-09-15 08:01
Second Decision
2020-09-24 14:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-25 05:26
Articles in Press
2020-09-25 05:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-10-09 02:06
Typeset the Manuscript
2020-11-12 02:19
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com