Publication Name	World Journal of Clinical Cases
Manuscript ID	59116
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Application of endoscopic submucosal dissection in duodenal space-occupying lesions
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Yu Li, Kai-Yue Ji, Yu-Hu Qu, Juan-Juan Zheng, Ying-jie Guo, Cui-ping Zhang and Kun-Peng Zhang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81802777 Shandong Higher Education Research Center Scientific Research Project YJKT201953 Shandong Province 2018 Professional Degree Postgraduate Teaching Case Library Project SDYAL18049 Shandong Province 2018 Postgraduate Mentoring Ability Improvement Project SDYY18073 "Clinical Medicine+X" project of Qingdao University Hospital
Corresponding Author	Kun-Peng Zhang, PhD, Doctor, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No 16 Jiangsu Road, Qingdao 266000, Shandong Province, China. zhangkp17@126.com
Key Words	Endoscopic resection; Submucosal dissection; Space-occupying lesions; Duodenal adenoma; Duodenal lesions; Complications
Core Tip	Endoscopic submucosal dissection (ESD) has been trusted by digestive endoscopists because of its therapeutic effect that is comparable to surgery, reduced trauma, faster recovery, and fewer complications. ESD on duodenum is challenging due to the thin intestinal wall of the duodenum, narrow intestinal space, rich peripheral blood flow, and proximity to vital organs, such as the common bile duct and pancreas. Therefore, the duodenal lesion biopsy before ESD should be small and parallel to the fold to avoid scarring and hindering subsequent dissection. Duodenal ESD should be performed quickly to shorten the operation time and reduce delayed perforation and bleeding caused by electrocoagulation syndrome and intestinal wall edema, especially when the lesions are on the medial side of the descending segment of duodenum because of in close proximity to huge arteries, the common bile duct and pancreas tissues. The wounds after ESD should be sutured with metal clips to avoid late perforation.
Citation	Li XY, Ji KY, Qu YH, Zheng JJ, Guo YJ, Zhang CP, Zhang KP. Application of endoscopic submucosal dissection in duodenal space-occupying lesions. World J Clin Cases 2020; 8(24): 6296-6305

Received	2020-08-26 22:55
Peer-Review Started	2020-08-26 22:55
To Make the First Decision
Return for Revision	2020-09-13 03:42
Revised	2020-09-15 14:47
Second Decision	2020-09-24 14:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-09-25 05:10
Articles in Press	2020-09-25 05:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-10-16 00:09
Typeset the Manuscript	2020-11-25 00:33

ISSN	2307-8960 (online)
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