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Publication Name World Journal of Stem Cells
Manuscript ID 59741
Country/Territory Brazil
Category Orthopedics
Manuscript Type Minireviews
Article Title Platelet-rich plasma vs bone marrow aspirate concentrate: An overview of mechanisms of action and orthobiologic synergistic effects
Manuscript Source Unsolicited Manuscript
All Author List José Fábio Santos Duarte Lana, Lucas Furtado da Fonseca, Rafael da Rocha Macedo, Tomas Mosaner, William Murrell, Ashok Kumar, Joseph Purita and Marco Antonio Percope de Andrade
Funding Agency and Grant Number
Corresponding Author José Fábio Santos Duarte Lana, MD, Chief Doctor, Surgeon, Department of Orthopedics, The Bone and Cartilage Institute, 1386 Presidente Kennedy Avenue, Indaiatuba 13334-170, SP, Brazil. josefabiolana@gmail.com
Key Words Orthobiologics; Platelet-rich plasma; Bone-marrow aspirate; Regenerative medicine; Musculoskeletal diseases; Stem cells
Core Tip Degenerative musculoskeletal disorders are one of the top causes of pain and disability in the adult population. The use of certain analgesics delivers short term results but do not address the etiological source of pain and disability. The demand for musculoskeletal tissue regeneration has led to an alternative approach referred to as orthobiologics, which is based on cellular and molecular components capable of promoting tissue repair. Platelet-rich plasma and bone marrow aspirate concentrate are popular orthobiologic products that may work synergistically in order to enhance the treatment of musculoskeletal conditions.
Citation Lana JFSD, da Fonseca LF, Macedo RDR, Mosaner T, Murrell W, Kumar A, Purita J, de Andrade MAP. Platelet-rich plasma vs bone marrow aspirate concentrate: An overview of mechanisms of action and orthobiologic synergistic effects. World J Stem Cells 2021; 13(2): 155-167
Received
2020-09-26 03:12
Peer-Review Started
2020-09-26 03:13
To Make the First Decision
Return for Revision
2020-11-03 21:50
Revised
2020-12-15 21:21
Second Decision
2021-01-05 02:50
Accepted by Journal Editor-in-Chief
2021-01-06 04:22
Accepted by Company Editor-in-Chief
2021-01-15 19:12
Articles in Press
2021-01-15 19:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-01-22 01:12
Typeset the Manuscript
2021-02-22 06:56
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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