Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	60730
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Functional transition: Inconsistently parallel to the increase in future liver remnant volume after preoperative portal vein embolization
Manuscript Source	Unsolicited Manuscript
All Author List	Yosuke Tsuruga, Toshiya Kamiyama, Hirofumi Kamachi, Tatsuya Orimo, Shingo Shimada, Akihisa Nagatsu, Yoh Asahi, Yuzuru Sakamoto, Tatsuhiko Kakisaka and Akinobu Taketomi
Funding Agency and Grant Number
Corresponding Author	Yosuke Tsuruga, MD, PhD, Doctor, Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan. ytsuruga@d2.dion.ne.jp
Key Words	Preoperative portal vein embolization; Hepatectomy; 99mTc-galactosyl-human serum albumin single-photon emission computed tomography; Future liver remnant volume; Functional transition; Fatty liver change
Core Tip	Preoperative portal vein embolization (PVE) induces hypertrophy of the future liver remnant (FLR) and a shift of the functional reserve to the FLR. However, whether the increase in FLR volume (FLRV) corresponds to the functional transition after PVE remains unclear. We investigated the sequential relationship between the increase in the FLRV and the functional transition after preoperative PVE. The functional transition lagged behind the increase in FLRV after PVE in 3 of the 33 cases. Evaluating both volume and function is needed to determine the optimal timing of hepatectomy after PVE.
Citation	Tsuruga Y, Kamiyama T, Kamachi H, Orimo T, Shimada S, Nagatsu A, Asahi Y, Sakamoto Y, Kakisaka T, Taketomi A. Functional transition: Inconsistently parallel to the increase in future liver remnant volume after preoperative portal vein embolization. World J Gastrointest Surg 2021; 13(2): 153-163

Received	2020-11-16 13:53
Peer-Review Started	2020-11-16 13:54
To Make the First Decision
Return for Revision	2020-12-20 03:36
Revised	2020-12-26 06:30
Second Decision	2021-01-08 04:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-01-14 17:54
Articles in Press	2021-01-14 17:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-02-04 00:36

ISSN	1948-9366 (online)
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