Publication Name	World Journal of Clinical Cases
Manuscript ID	60823
Country	China

Category	Otorhinolaryngology
Manuscript Type	Case Report
Article Title	Laryngopharyngeal reflux disease management for recurrent laryngeal contact granuloma: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Kai Li, Wen-Yong Chen, Yun-Ying Li, Tu-Lu Wang, Meng-Jia Tan, Zong Chen and Hai Chen
Funding Agency and Grant Number
Corresponding Author	Hai Chen, MM, Assistant Professor, Doctor, Otorhinolaryngology, The Second Clinical College of Guangzhou University of Chinese Medicine, Dade Road, Yuexiu District, Guangzhou 510000, Guangdong Province, China. cnchenhai@gzucm.edu.cn
Key Words	Recurrent laryngeal contact granuloma; Laryngopharyngeal reflux disease management; Anti-reflux therapy; Pepsin secretion inhibition; Bile acid neutralization; Case report
Core Tip	Laryngeal contact granuloma (LCG) is difficult to treat and frequently associated with high persistence and recurrence. Here, we describe a patient with recurrent LCG in which a good response was achieved through successful management of laryngopharyngeal reflux disease using a combination pharmacotherapeutic regimen consisting of anti-reflux therapy, pepsin secretion inhibition, bile acid neutralization, and lifestyle modifications. The drug regimen was ended after one year, and no recurrence throughout the one-year follow-up period. The case report highlights the efficacy of the combined pharmacotherapeutic and lifestyle modifications in managing laryngopharyngeal reflux disease to address recurring LCG.
Citation	Li K, Chen WY, Li YY, Wang TL, Tan MJ, Chen Z, Chen H. Laryngopharyngeal reflux disease management for recurrent laryngeal contact granuloma: A case report. World J Clin Cases 2021; 9(8): 1989-1995

Received	2020-11-20 15:07
Peer-Review Started	2020-11-16 12:13
To Make the First Decision
Return for Revision	2020-12-24 15:26
Revised	2021-01-05 15:51
Second Decision	2021-01-08 13:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-01-08 17:15
Articles in Press	2021-01-08 17:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-01-27 05:29
Typeset the Manuscript	2021-02-26 10:14

ISSN	2307-8960 (online)
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