Publication Name	World Journal of Clinical Cases
Manuscript ID	61156
Country	Taiwan

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Chest pain in a heart transplant recipient: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Jen Chen, Chien-Sung Tsai and Tsai-Wang Huang
Funding Agency and Grant Number
Corresponding Author	Tsai-Wang Huang, PhD, Associate Professor, Attending Doctor, Chief Doctor, Division of Thoracic Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325,Sec.2,Chenggong Road, Neihu District, Taipei 11490, Taiwan. chi-wang@yahoo.com.tw
Key Words	Heart transplantation; Refractory heart failure; Chest pain; Achalasia; Esophagogram; Case report
Core Tip	Chest pain after heart transplantation usually present with noncardiac symptoms due to the denervated heart. Its differential diagnosis includes acute allograft dysfunction caused by acute myocardial infarction, myocarditis, hypertensive crisis, or infections. However, data from case reports on tacrolimus-induced achalasia after heart transplantation are limited. In this case involving a rare complication of tacrolimus-induced achalasia after heart transplantation, we successfully treated the patient with laparoscopic Heller myotomy. This case highlights that calcineurin inhibitor -induced achalasia should be considered in transplant patients with atypical chest pain. Esophagogram or manometry may be helpful for its diagnosis.
Citation	Chen YJ, Tsai CS, Huang TW. Chest pain in a heart transplant recipient: A case report. World J Clin Cases 2021; 9(16): 3966-3970

Received	2020-11-26 07:41
Peer-Review Started	2020-11-26 07:41
To Make the First Decision
Return for Revision	2021-01-24 04:15
Revised	2021-01-26 16:39
Second Decision	2021-04-12 12:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-12 16:21
Articles in Press	2021-04-12 16:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-05-11 05:44

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com