Publication Name	World Journal of Gastroenterology
Manuscript ID	61426
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis
Manuscript Source	Unsolicited Manuscript
All Author List	Peng Deng, Ming Sun, Wen-Yan Zhao, Bin Hou, Kai Li, Tao Zhang and Feng Gu
Funding Agency and Grant Number
Corresponding Author	Feng Gu, PhD, Chief Physician, Department of Ophthalmology, The First Affiliated Hospital of China Medical University, No. 155 Nanjing North street, Heping District, Shenyang 110001, Liaoning Province, China. fenggu78186069@163.com
Key Words	Gastric cancer; Progression; Chemoresistance; CircVAPA; miR-125b-5p; STAT3
Core Tip	We concluded that circVAPA contributed to chemotherapy resistance and malignant progression of gastric cancer (GC) by miR-125b-5p/STAT3 signaling. Our findings present novel insights into the mechanism that circVAPA regulates chemotherapy resistance of GC. CircVAPA and miR-125b-5p may be considered as potential targets for GC therapy.
Citation	Deng P, Sun M, Zhao WY, Hou B, Li K, Zhang T, Gu F. Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis. World J Gastroenterol 2021; 27(6): 487-500

Received	2020-12-06 13:00
Peer-Review Started	2020-12-06 13:02
To Make the First Decision
Return for Revision	2020-12-17 20:02
Revised	2020-12-21 11:05
Second Decision	2021-01-07 12:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-01-07 19:12
Articles in Press	2021-01-07 19:12
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-01-24 08:26
Typeset the Manuscript	2021-02-03 02:21

ISSN	1007-9327 (print) and 2219-2840 (online)
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