Publication Name	World Journal of Radiology
Manuscript ID	61729
Country	United Kingdom

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Evidence Review
Article Title	Discrepancies in the clinical and radiological profiles of COVID-19: A case-based discussion and review of literature
Manuscript Source	Invited Manuscript
All Author List	Hemant Kumar, Cornelius James Fernandez, Sangheetha Kolpattil, Mohamed Munavvar and Joseph M Pappachan
Funding Agency and Grant Number
Corresponding Author	Joseph M Pappachan, FRCP (Hon), MD, Consultant Physician-Scientist, Professor, Senior Researcher, Department of Medicine & Endocrinology , Lancashire Teaching Hospitals NHS Trust, Sharow Green Lane, Preston PR2 9HT, United Kingdom. drpappachan@yahoo.co.in
Key Words	COVID-19; Pneumonia; Lung imaging; Chest X-ray; Computed tomography; Lung ultrasound
Core Tip	The coronavirus disease-19 (COVID-19) pandemic has had a devastating impact on the human race, with the current death toll exceeding 2.8 million. Although a positive reverse transcriptase polymerase chain reaction test is the gold standard for diagnosing a COVID-19 infection, the reported sensitivity of the test is < 90%, and clinicians often need to rely upon various imaging studies for definitive diagnoses and prognostication. However, discrepancies between the clinical and imaging profiles of patients with the disease can often pose challenges in therapeutic decision making. Therefore, it is imperative to understand the diagnostic sensitivity, specificity, and positive and negative predictive values of each imaging modality for the rational management of patients with this enigmatic disease. This evidence-based review is a clinical update to empower clinicians across the world who is involved in combatting COVID-19.
Citation	Kumar H, Fernandez CJ, Kolpattil S, Munavvar M, Pappachan JM. Discrepancies in the clinical and radiological profiles of COVID-19: A case-based discussion and review of literature. World J Radiol 2021; 13(4): 75-93

Received	2020-12-16 19:43
Peer-Review Started	2020-12-16 19:45
To Make the First Decision
Return for Revision	2021-03-31 05:38
Revised	2021-04-03 08:35
Second Decision	2021-04-13 10:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-13 18:45
Articles in Press	2021-04-13 18:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-04-21 00:58

ISSN	1949-8470 (online)
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