Publication Name	World Journal of Diabetes
Manuscript ID	61790
Country	Italy

Category	Public, Environmental & Occupational Health
Manuscript Type	Observational Study
Article Title	Relationships between emissions of toxic airborne molecules and type 1 diabetes incidence in children: An ecologic study
Manuscript Source	Invited Manuscript
All Author List	Agostino Di Ciaula and Piero Portincasa
Funding Agency and Grant Number
Corresponding Author	Agostino Di Ciaula, MD, Academic Fellow, Academic Research, Doctor, Medical Assistant, Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, P.zza Giulio Cesare 11, Bari 70124, Italy. agostinodiciaula@tiscali.it
Key Words	Type 1 diabetes; Epidemiology; Air pollution; Particulate matter; Nitrogen oxide; Non-methane volatile organic compounds
Core Tip	The environment has a role in the onset of type 1 diabetes. Possible associations include pollutants which, however, are scarcely explored. We evaluated with an ecologic approach associations between the incidence of type 1 diabetes in children, and the global emissions of specific air pollutants in 19 European countries, during three decades. We showed that the incidence of type 1 diabetes is associated with the emissions of particulates < 10 μm, non-methane volatile organic compounds, and nitrogen oxide. Results allow us to speculate that type 1 diabetes is, at least in part, a preventable condition, with implications in terms of primary prevention.
Citation	Di Ciaula A, Portincasa P. Relationships between emissions of toxic airborne molecules and type 1 diabetes incidence in children: An ecologic study. World J Diabetes 2021; 12(5): 673-684

Received	2020-12-18 19:13
Peer-Review Started	2020-12-18 19:15
To Make the First Decision
Return for Revision	2021-03-16 06:46
Revised	2021-03-17 21:38
Second Decision	2021-04-12 12:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-12 18:19
Articles in Press	2021-04-12 18:19
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-04-15 18:28
Typeset the Manuscript	2021-04-30 03:15

ISSN	1948-9358 (online)
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