Publication Name	World Journal of Gastroenterology
Manuscript ID	63488
Country	Romania

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Could the burden of pancreatic cancer originate in childhood?
Manuscript Source	Invited Manuscript
All Author List	Smaranda Diaconescu, Georgiana Emmanuela Gîlcă-Blanariu, Silvia Poamaneagra, Otilia Marginean, Gabriela Paduraru and Gabriela Stefanescu
Funding Agency and Grant Number
Corresponding Author	Smaranda Diaconescu, MD, PhD, Professor, Department of Pediatrics, “Grigore T. Popa” University Of Medicine and Pharmacy, 16 Universității str, Iasi 700115, Romania. turti23@yahoo.com
Key Words	Pancreatic cancer; Pancreatic metastasis; Childhood; Adult; Screening; Transition
Core Tip	Pancreatic malignant tumors are rarely found during childhood, their prognosis being linked to the type of tumor and its capacity to evolve towards metastasis. Also, there are types of cancer diagnosed in pediatric patients which may present with pancreatic metastasis later, during adulthood. Various conditions, when diagnosed during childhood, may be associated with the later onset of pancreatic cancer. Also, several genetic mutations have been linked to the development of pancreatic malignancies. We discuss here the above-mentioned topics in the context of a comprehensive literature review.
Citation	Diaconescu S, Gîlcă-Blanariu GE, Poamaneagra S, Marginean O, Paduraru G, Stefanescu G. Could the burden of pancreatic cancer originate in childhood? World J Gastroenterol 2021; 27(32): 5322-5340

Received	2021-01-28 19:59
Peer-Review Started	2021-01-28 20:04
To Make the First Decision
Return for Revision	2021-05-13 01:17
Revised	2021-06-08 19:32
Second Decision	2021-07-30 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-30 07:04
Articles in Press	2021-07-30 07:04
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-08-10 06:12
Typeset the Manuscript	2021-08-24 01:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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