Publication Name	World Journal of Hepatology
Manuscript ID	64284
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Systematic Reviews
Article Title	Incidence of umbilical vein catheter-associated thrombosis of the portal system: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Iliana Bersani, Fiammetta Piersigilli, Giulia Iacona, Immacolata Savarese, Francesca Campi, Andrea Dotta, Cinzia Auriti, Enrico Di Stasio and Matteo Garcovich
Funding Agency and Grant Number
Corresponding Author	Enrico Di Stasio, MD, PhD, Academic Research, Doctor, Department of Biochemistry and Clinical Biochemistry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo gemelli 8, Roma 00168, Italy. enrico.distasio@unicatt.it
Key Words	Portal vein thrombosis; Umbilical venous catheter; Portal system thrombosis; Hepatic thrombosis; Neonate; Incidence
Core Tip	Portal vein thrombosis (PVT) is a dreadful complication that can occur after umbilical vein catheterization in neonates. Although previous observational studies have provided a general overview about the risk of this complication, the present systematic review specifically investigates the incidence catheter-related PVT and identifies relevant gaps in knowledge about the optimal diagnostic approach highlighting the need for prospective randomized studies and updated guidelines.
Citation	Bersani I, Piersigilli F, Iacona G, Savarese I, Campi F, Dotta A, Auriti C, Di Stasio E, Garcovich M. Incidence of umbilical vein catheter-associated thrombosis of the portal system: A systematic review and meta-analysis. World J Hepatol 2021; 13(11): 1802-1815

Received	2021-03-21 17:00
Peer-Review Started	2021-03-21 17:04
To Make the First Decision
Return for Revision	2021-08-18 02:17
Revised	2021-08-31 07:32
Second Decision	2021-10-12 08:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-10-14 03:00
Articles in Press	2021-10-14 03:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-11-19 00:50

ISSN	1948-5182 (online)
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