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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 64606
Country/Territory South Korea
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Evaluating the benefit of adjuvant chemotherapy in patients with ypT0–1 rectal cancer treated with preoperative chemoradiotherapy
Manuscript Source Invited Manuscript
All Author List Ye Won Jeon, In Ja Park, Jeong Eun Kim, Jin-Hong Park, Seok-Byung Lim, Chan Wook Kim, Yong Sik Yoon, Jong Lyul Lee, Chang Sik Yu and Jin Cheon Kim
Funding Agency and Grant Number
Corresponding Author In Ja Park, MD, PhD, Doctor, Professor, Surgeon, Deparrment of Colon and Rectal Surgery, Asan Medical Center and University of Ulsan College of Medicine, No. 88 Olympic-ro, Songpa-gu, Seoul 05505, South Korea. ipark@amc.seoul.kr
Key Words Rectal neoplasm; Adjuvant chemotherapy; ypT0-1; Radical resection; Local excision
Core Tip Adjuvant chemotherapy (ACTx) is administered based on the clinical stage of rectal cancer after preoperative chemoradiotherapy (PCRT), regardless of post-treatment pathologic stage. Prognosis differs according to post-treatment pathologic stage or regression grade. Adjuvant treatment may be administered based on prognostic influence. Patients with ypT0-1 rectal cancer with favorable oncologic outcomes were included. Since local excision (LE) frequency has increased, ACTx effects in these patients need to be studied. We included patients who underwent LE. ACTx in patients with ypT0-1 rectal cancer after PCRT and LE did not exert benefits in terms of overall survival and recurrence-free survival.
Citation Jeon YW, Park IJ, Kim JE, Park JH, Lim SB, Kim CW, Yoon YS, Lee JL, Yu CS, Kim JC. Evaluating the benefit of adjuvant chemotherapy in patients with ypT0–1 rectal cancer treated with preoperative chemoradiotherapy. World J Gastrointest Surg 2021; 13(9): 1000-1011
Received
2021-02-21 04:34
Peer-Review Started
2021-02-21 04:37
To Make the First Decision
Return for Revision
2021-05-22 02:43
Revised
2021-05-22 15:14
Second Decision
2021-08-02 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-02 08:46
Articles in Press
2021-08-02 08:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-09-17 01:18
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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