Publication Name	World Journal of Hepatology
Manuscript ID	65138
Country	Thailand

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Cytomegalovirus infection in liver-transplanted children
Manuscript Source	Invited Manuscript
All Author List	Norrapat Onpoaree, Anapat Sanpawat and Palittiya Sintusek
Funding Agency and Grant Number
Corresponding Author	Palittiya Sintusek, MD, MSc, Assistant Professor, Lecturer, Thai Paediatric Gastroenterology, Hepatology and Immunology Research Unit, Chulalongkorn University, 1873 Rama IV Road, Pathum Wan, Bangkok 10330, Thailand. palittiya.s@chula.ac.th
Key Words	Cytomegalovirus; Children; Liver transplantation; Pediatric; Infection
Core Tip	Cytomegalovirus (CMV) infection after liver transplantation in children is a serious complication, with high morbidity resulting from direct and indirect effects. Despite risk stratification, pre-emptive therapy and antiviral prophylaxis, late CMV infection frequently occurs in transplant recipients. If CMV infection is suspected during outpatient visits, then prompt detection is key. If CMV infection is detected, then decreasing immunosuppressants should be prioritized before initiation of antiviral therapy. Oral valganciclovir and intravenous ganciclovir are the mainstays of treatment, with variable duration depending on CMV manifestations, viral load, histopathology, and clinical response.
Citation	Onpoaree N, Sanpawat A, Sintusek P. Cytomegalovirus infection in liver-transplanted children. World J Hepatol 2022; 14(2): 338-353

Received	2021-02-28 13:46
Peer-Review Started	2021-02-28 14:04
To Make the First Decision
Return for Revision	2021-03-29 16:18
Revised	2021-04-17 08:20
Second Decision	2022-01-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-01-17 05:35
Articles in Press	2022-01-17 05:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-02-10 09:54

ISSN	1948-5182 (online)
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