Publication Name	World Journal of Gastroenterology
Manuscript ID	66092
Country	Brazil

Category	Gastroenterology & Hepatology
Manuscript Type	Frontier
Article Title	Helicobacter pylori infection: How does age influence the inflammatory pattern?
Manuscript Source	Invited Manuscript
All Author List	Glauber Rocha Lima Araújo, Hanna Santos Marques, Maria Luísa Cordeiro Santos, Filipe Antônio França da Silva, Breno Bittencourt de Brito, Gabriel Lima Correa Santos and Fabrício Freire de Melo
Funding Agency and Grant Number
Corresponding Author	Fabrício Freire de Melo, PhD, Professor, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Instituto Multidisciplinar em Saúde, Universidade Federal da Bahia, Rua Hormindo Barros, 58, Quadra 17, Lote 58, Vitória da Conquista 45029-094, Bahia, Brazil. , Vitória da Conquista 45029-094, Bahia, Brazil. freiremelo@yahoo.com.br
Key Words	Helicobacter pylori; Inflammation; Treg response; Th1 response; Th17 response; Gastric diseases
Core Tip	Helicobacter pylori (H. pylori) is a bacterium acquired mainly in childhood that increases the risk of developing certain gastric diseases. However, the main complications are noticed predominantly in adulthood. This can be explained based on the gastric inflammatory pattern against the pathogen, which changes as long as the infected individual gets older, favoring, during childhood, the persistence of the infection and then, in adulthood, the gastric damage. This article discusses the factors that can influence the gastric inflammatory pattern in individuals infected with H. pylori.
Citation	Araújo GRL, Marques HS, Santos MLC, da Silva FAF, de Brito BB, Correa Santos GL, de Melo FF. Helicobacter pylori infection: How does age influence the inflammatory pattern? World J Gastroenterol 2022; 28(4): 402-411

Received	2021-03-20 20:19
Peer-Review Started	2021-03-20 20:22
To Make the First Decision
Return for Revision	2021-06-14 04:15
Revised	2021-06-21 13:20
Second Decision	2022-01-12 03:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-01-12 21:45
Articles in Press	2022-01-12 21:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-12-29 00:22
Typeset the Manuscript	2022-01-13 09:18

ISSN	1007-9327 (print) and 2219-2840 (online)
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