Publication Name	World Journal of Gastroenterology
Manuscript ID	67692
Country	South Korea

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Tailored eradication strategy vs concomitant therapy for Helicobacter pylori eradication treatment in Korean patients
Manuscript Source	Invited Manuscript
All Author List	Youn I Choi, Jun-Won Chung, Kyoung Oh Kim, Kwang An Kwon, Yoon Jae Kim, Jung Ho Kim, Ja Young Seo and Dong Kyun Park
Funding Agency and Grant Number	Funding Agency Grant Number National Research Foundation of Korea (NRF) funded by the Ministry of Education NRF-2020R1F1A1076839
Corresponding Author	Jun-Won Chung, MD, PhD, Professor, Division of Internal Medicine, Department of Gastroenterology, Gachon University College of Medicine, Gil medical Center, 21 Namdong-daero 774beon-gil, Namdong-gu, Incheon 21565, South Korea. junwonchung@hanmail.net
Key Words	Helicobacter pylori; Eradication; Tailored therapy; Concomitant therapy regimen
Core Tip	We investigated the efficacy and safety profiles of a tailored therapy (TT) as a first line Helicobacter pylori (H. pylori) eradication treatment compared to a concomitant therapy (CT) regimen in Korea, where clarithromycin resistance rates are high. Of 217 treatment-naïve H. pylori infection patients, 107 patients were treated with CT and 101 patients with TT. Although the eradication success rate was not statistically different between the groups, the treatment-related side effect rate was significantly lower in the TT group. Therefore, the TT regimen might be a promising solution to overcoming the problem of increased antibiotic resistance rates for Helicobacter eradication.
Citation	Choi YI, Chung JW, Kim KO, Kwon KA, Kim YJ, Kim JH, Seo JY, Park DK. Tailored eradication strategy vs concomitant therapy for Helicobacter pylori eradication treatment in Korean patients. World J Gastroenterol 2021; 27(31): 5247-5258

Received	2021-04-29 06:14
Peer-Review Started	2021-04-29 06:17
To Make the First Decision
Return for Revision	2021-06-03 03:41
Revised	2021-07-09 13:52
Second Decision	2021-07-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-29 08:42
Articles in Press	2021-07-29 08:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-08-15 14:31

ISSN	1007-9327 (print) and 2219-2840 (online)
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