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Publication Name World Journal of Gastroenterology
Manuscript ID 67709
Country/Territory Italy
Category Biotechnology & Applied Microbiology
Manuscript Type Review
Article Title Over-feeding the gut microbiome: A scoping review on health implications and therapeutic perspectives
Manuscript Source Invited Manuscript
All Author List Monica Barone, Federica D'Amico, Marco Fabbrini, Simone Rampelli, Patrizia Brigidi and Silvia Turroni
Funding Agency and Grant Number
Corresponding Author Silvia Turroni, PhD, Associate Professor, Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Via Belmeloro 6, Bologna 40126, Italy. silvia.turroni@unibo.it
Key Words Gut microbiome; Microbial metabolites; Obesity; Next-generation probiotics; Fecal microbiota transplantation; Deep learning
Core Tip The gut microbiome (GM) has gained increasing attention in recent years due to its key role in contributing to host health, potentially serving as a target for personalized precision medicine. This review summarizes the current evidence for the involvement of the GM in the regulation of various pathophysiological aspects, particularly in obesity and related comorbidities. The influence of diet and the molecules produced by commensal microorganisms is discussed, together with traditional and innovative microbiome-based strategies in the prevention and treatment of obesity, up to the development of machine and deep learning bioinformatics tools for the prediction of health risks and therapeutic outcomes.
Citation Barone M, D'Amico F, Fabbrini M, Rampelli S, Brigidi P, Turroni S. Over-feeding the gut microbiome: A scoping review on health implications and therapeutic perspectives. World J Gastroenterol 2021; 27(41): 7041-7064
Received
2021-04-29 13:53
Peer-Review Started
2021-04-29 13:55
To Make the First Decision
Return for Revision
2021-06-17 02:16
Revised
2021-07-02 16:15
Second Decision
2021-10-12 08:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-10-14 02:56
Articles in Press
2021-10-14 02:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-09-23 08:51
Typeset the Manuscript
2021-10-29 08:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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