Publication Name	World Journal of Nephrology
Manuscript ID	68166
Country	Kenya

Category	Urology & Nephrology
Manuscript Type	Observational Study
Article Title	Concordance between bio-impedance analysis and clinical score in fluid-status assessment of maintenance haemodialysis patients: A single centre experience
Manuscript Source	Invited Manuscript
All Author List	Kamiti Muchiri, Joshua K Kayima, Elijah N Ogola, Seth McLigeyo, Sally W Ndung’u and Samuel K Kabinga
Funding Agency and Grant Number
Corresponding Author	Samuel K Kabinga, MBChB, MD, Doctor, East African Kidney Institute, University of Nairobi, P.O. Box 30197, Nairobi +254, Kenya. kabingas@yahoo.com
Key Words	Bio-impedance analysis; Clinical score; Chronic kidney disease; Maintenance haemodialysis; Fluid overload; Concordance
Core Tip	Bio-impedance analysis (BIA) has been validated as an accurate and reliable tool for determining fluid status in chronic kidney disease (CKD) patients but is not widely available in low-income settings. In this study we assess how a clinical score (CS) compares with BIA in this population for possible use as a low-cost substitute where BIA is not available. Patients with a CS score greater than 4 were considered to have fluid overload (FO), and detected using this parameter in 58.75% of patients. CSs of ≤ 4 represented no FO, and represented 41.25% of patients. The CS had a sensitivity of 63% and a specificity of 78% in making a diagnosis of FO compared with BIA, which was used as the reference in patients with CKD on maintenance haemodialysis.
Citation	Muchiri K, Kayima JK, Ogola EN, McLigeyo S, Ndung’u SW, Kabinga SK. Concordance between bio-impedance analysis and clinical score in fluid-status assessment of maintenance haemodialysis patients: A single centre experience. World J Nephrol 2022; 11(4): 127-138

Received	2021-06-19 07:30
Peer-Review Started	2021-06-19 07:33
To Make the First Decision
Return for Revision	2021-07-31 04:18
Revised	2021-09-19 16:16
Second Decision	2022-06-20 03:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-27 00:41
Articles in Press	2022-06-27 00:41
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-06-07 19:54
Typeset the Manuscript	2022-07-07 12:13

ISSN	2220-6124 (online)
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