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1/17/2022 5:32:55 AM | Browse: 94 | Download: 189
Publication Name World Journal of Psychiatry
Manuscript ID 69371
Country United Kingdom
Category Geriatrics & Gerontology
Manuscript Type Retrospective Cohort Study
Article Title Associated mortality risk of atypical antipsychotic medication in individuals with dementia
Manuscript Source Unsolicited Manuscript
All Author List Peter Phiri, Tomas Engelthaler, Hannah Carr, Gayathri Delanerolle, Clive Holmes and Shanaya Rathod
Funding Agency and Grant Number
Corresponding Author Peter Phiri, BSc, PhD, RN, Academic Fellow, Research & Innovation Department, Southern Health NHS Foundation Trust, Botley Road, West End, Southampton SO30 3JB, United Kingdom. peter.phiri@southernhealth.nhs.uk
Key Words Dementia; Antipsychotics; Mortality; Vascular; Alzheimer’s disease; Frontotemporal dementia; Lewy bodies; Parkinson’s and mixed
Core Tip Antipsychotic medication is widely prescribed to patients with dementia displaying neuropsychiatric symptoms. Treatment with olanzapine and risperidone was associated with an increased mortality risk. In comparison, quetiapine showed a relatively lower, non-significant association with the mortality risk in those with dementia. Clinicians need to be aware of the potential heterogeneous relationship between dementias, antipsychotic medication, and mortality when creating a psychopharmacological treatment plan for their patients.
Citation Phiri P, Engelthaler T, Carr H, Delanerolle G, Holmes C, Rathod S. Associated mortality risk of atypical antipsychotic medication in individuals with dementia. World J Psychiatry 2022; 12(2): 298-307
Received
2021-06-28 12:32
Peer-Review Started
2021-06-28 12:37
To Make the First Decision
Return for Revision
2021-09-05 21:05
Revised
2021-09-24 02:34
Second Decision
2022-01-15 02:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-17 05:32
Articles in Press
2022-01-17 05:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-02-09 08:12
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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