Publication Name	World Journal of Meta-Analysis
Manuscript ID	74227
Country	India

Category	Orthopedics
Manuscript Type	Meta-Analysis
Article Title	Evidence analysis on the utilization of platelet-rich plasma as an adjuvant in the repair of rotator cuff tears
Manuscript Source	Invited Manuscript
All Author List	Sathish Muthu, Naveen Jeyaraman, Keval Patel, Girinivasan Chellamuthu, Vibhu Krishnan Viswanathan, Madhan Jeyaraman and Manish Khanna
Funding Agency and Grant Number
Corresponding Author	Madhan Jeyaraman, MS, PhD, Assistant Professor, Research Associate, Department of Orthopaedics, Faculty of Medicine, Sri Lalithambigai Medical College and Hospital, Dr MGR Educational and Research Institute, Madhuravoyal, Chennai 600095, Tamil Nadu , India. madhanjeyaraman@gmail.com
Key Words	Platelet-rich plasma; Rotator cuff tears; Meta-analyses; Functional outcome; Re-tear; Recommendation
Core Tip	Platelet-rich plasma has been gaining popularity as an agent for biological augmentation either as the sole treatment modality or as an adjunct to surgical repair. There is growing evidence on the positive effects of platelet-derived autologous growth factors on collagen production, cell proliferation, tissue revascularization and tendon regeneration thereby making them useful as an augment to arthroscopic rotator cuff repair. Based on our analysis, we found that the intra-operative use of PRPs at the bone-tendon interface can augment the healing rate, reduce re-tears, enhance functional outcome and mitigate pain in patients undergoing arthroscopic rotator cuff repair.
Citation	Muthu S, Jeyaraman N, Patel K, Chellamuthu G, Viswanathan VK, Jeyaraman M, Khanna M. Evidence analysis on the utilization of platelet-rich plasma as an adjuvant in the repair of rotator cuff tears. World J Meta-Anal 2022; 10(3):143-161

Received	2021-12-18 00:09
Peer-Review Started	2021-12-18 00:10
To Make the First Decision
Return for Revision	2022-03-13 23:12
Revised	2022-03-23 16:45
Second Decision	2022-06-20 03:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-26 23:35
Articles in Press	2022-06-26 23:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-26 21:22
Typeset the Manuscript	2022-06-27 10:16

ISSN	2308-3840 (online)
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